Searchable abstracts of presentations at key conferences in endocrinology

ea0081p349 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

User acceptance and satisfaction with the eversense XL CGM in patients with type 1 diabetes

Javier Martinez Martin Francisco , Hernandez-Lazaro Alba , de Leon-Durango Ricardo , Kuzior Agnieszka , Arnas-Leon Claudia , Acosta-Calero Carmen

Objectives: Eversense XL is a fully implantable sensor for continuous glucose monitoring (CGM) that lasts for up to 180 days. Our objective was to perform a survey on user acceptance and satisfaction among our type 1 diabetic patients who had been using the Eversense XL CGM for at least 3 months.Methods: A questionnaire was devised in which the patients were asked about their experience with the Eversense XL CGM, including:-Compari...

ea0081ep1086 | Thyroid | ECE2022

Failure of rhTSH-stimulated FDG PET-CT scan to identify metastases of a papillary thyroid carcinoma

de Leon-Durango Ricardo , Hernandez-Lazaro Alba , Acosta-Calero Carmen , Kuzior Agnieszka , Arnas-Leon Claudia , Javier Martinez Martin Francisco

Introduction: Recurrences of differenciated thyroid carcinoma are occasionally hard to locate; rhTSH-stimulated FDG PET-CT may offer a higher sensitivity, particularly when thyroglobulin in high, but its utility has not been clearly established. Methods: Review of the patient’s clinical record Results: A 61 years old woman noticed a right anterior neck lump when she was 47; FNAC was suggestive of a solid papillary thyroid carc...

ea0084ps2-10-96 | Nodules & Cancer | ETA2022

Prospective, observational study on radioiodine treatment in DTC patients with intermediate RISK or micro lymph node metastases

Blewaska Aleksandra , Ledwon Aleksandra , Paliczka-Cieslik Ewa , Sygula Aleksandra , Haras-Gil Malgorzata , Kropinska Aleksandra , Czarniecka Agnieszka , Handkiewicz-Junak Daria

There are much controversy adjuvant radioiodine treatment (131-I-th) in intermediate or low risk patients with lymph node micrometastases. The first results of ESTIMABL2 trial showed no radioiodine benefit in low risk DTC, however intermediate patients were not included in this study.Aim: Observational study was to evaluate effects of 131-I-th in intermediate/low risk DTC patients.Patients: There were 342 women (85%), the median ag...

ea0090p722 | Reproductive and Developmental Endocrinology | ECE2023

Comparison of omentin (intelectin-1) expression and regulation in ovarian follicle cells from normal weight Large White and obese Meishan pigs

Pich Karolina , Respekta Natalia , Kurowska Patrycja , Rame Christelle , Dupont Joelle , Dobrzyń Kamil , Smolińska Nina , Rak Agnieszka

Introduction: Omentin, also known as intelectin-1 (ITLN1), is a novel adipokine produced predominantly by visceral adipose tissue, which improves insulin sensitivity. Decreased levels of ITLN1 have been reported in the serum of obese and polycystic ovary syndrome patients, as well as in the serum and adipose tissue of obese Meishan (MS) compared to normal weight Large White (LW) pigs. However, the role of ITLN1 in female reproduction at different metabolic status is still unkn...

ea0090p727 | Reproductive and Developmental Endocrinology | ECE2023

Resistin as A New Regulator of Luteolysis: in Vitro Effect of Resistin on Proliferation, Apoptosis, and Autophagy in Porcine Luteal Cells

Kurowska Patrycja , Gaździk Kinga , Jasińska Agata , Mlyczyńska Ewa , Wachowska Dominika , Rak Agnieszka

To maintain proper fertility the balance between formation and luteolysis of corpus luteum (CL) are necessary and strictly controlled events in female reproduction. Degeneration of CL is correlated with apoptosis and autophagy as well as connected with decreased progesterone (P4) level. Resistin is a new key player in the regulation of luteal cells function; our previously study showed that resistin have negative effect on P4 synthesis. Thus the aim of the present study was to...

ea0090ep438 | Diabetes, Obesity, Metabolism and Nutrition | ECE2023

The influence of the endocrinologist in the management of type 2 diabetes

Martinez Silvia Gonzalez , Escobedo Raul Rodriguez , Kuzior Agnieszka , Montero Paula Aristegui , Ojeda Aida Saavedra , Martin Roque Daniel

Introduction: In Spain, the specialist in endocrinology and nutrition is the reference in the care of patients with diabetes mellitus. In the year 2022, access to these specialists has been facilitated in the south of Gran Canaria. The aim of the study is to determine how this has influenced the management of type 2 diabetes (T2D).Methods: We included those patients with T2D assessed by the Endocrinology service in 2022 in which two analyses were perform...

ea0090ep699 | Pituitary and Neuroendocrinology | ECE2023

Pathologic characteristics of somatotroph pituitary tumors – an observational single-center study

Tomasik Agnieszka , Stelmachowska-Banaś Maria , Maksymowicz Maria , Czajka-Oraniec Izabella , Dorota Raczkiewicz , Zgliczyński Wojciech

Background: The first-line treatment in acromegaly is transsphenoidal adenomectomy of GH-secreting pituitary tumor. Pathologic evaluation of postoperative tissue is an essential part of patient’s assessment.Aim: The aim of this study was to analyse pathologic characteristics of pituitary tumors in patients with acromegaly.Patients and methods: One hundred twenty patients with acromegaly after at least one pituitary surgery tre...

ea0090ep1089 | Late Breaking | ECE2023

Influence of muscle mass and strength on bone mineralization with consideration of sclerostin concentration

Patalong-Wojcik Martyna , Sowińska-Przepiera Elżbieta , Malczyk-Matysiak Kinga , Myszka Aleksandra , Janiec Agnieszka , Syrenicz Anhelli

Introduction: Osteoporosis is a disease characterized by a decreased bone strength, as a result of increased bone porosity and impaired mineralization. According to the mechanostat theory, loads generated by the muscle mass and muscle strength, stimulate bone reconstruction.Aim of the study: In our study, we investigated whether muscle strength and mass exert a significant effect on bone mineral density in young adult women. We also tested whether sclero...

ea0067o15 | Oral Presentations | EYES2019

Aldosterone-to-renin ratio as an accurate diagnostic tool in patients on antihypertensive therapy

Łebek-Szatańska Agnieszka , Glinicki Piotr , Nowak Karolina M , Rdzanek Monika , Zgliczyński Wojciech , Papierska Lucyna

Objective: Withdrawal of the medications prior to screening for primary aldosteronism is problematic, sometimes impossible and probably not necessary as the routine practice. The aim of this study was to evaluate diagnostic accuracy of aldosterone-to-renin ratio in hypertensive patients undergoing laboratory screening for primary aldosteronism without obligatory drug modifications.Methods: Plasma aldosterone and direct renin concentrations from 20 patien...

ea0063gp51 | Acromegaly and GH | ECE2019

Prognostic value of short-acting pasireotide test for response prediction to pasireotide LAR in patients with acromegaly resistant to first-generation analogs. Can a short-acting pasireotide test predict the response of long-acting pasireotide treatment in patients with acromegaly resistant to first generation somatostatin analogs?

Majos Agnieszka , Stelmachowska-Banaś Maria , Czajka-Oraniec Izabella , Gęsior Jakub , Zgliczyński Wojciech

Introduction: The treatment of choice in acromegaly is a transsphenoidal surgery of a growth hormone (GH) - producing pituitary adenoma. In patients with persistent acromegaly after surgery medical treatment is recommended. First generation somatostatin analogs: lanreotide autogel and octreotide LAR are effective in 25% to 45% of patients depending on population and study protocol. Second-generation somatostatin analog – pasireotide LAR seems to be more effective. The pos...